E-ISSN 2980-2156
Formerly
Erciyes Medical Journal
Volume : 45 Issue : 6
Erciyes Medical Journal Skull Base Osteomyelitis Complicating COVID-19: A Novel Secondary Infection? [J Clin Pract Res]
J Clin Pract Res. 2023; 45(6): 651-654 | DOI: 10.14744/cpr.2023.77486

Skull Base Osteomyelitis Complicating COVID-19: A Novel Secondary Infection?

Emel Tahir1, Heval Can Bilek2, Emre Demirel1, Sinan Atmaca1
1Department of Otorhinolaryngology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye
2Department of Infectious Diseaes and Clinical Microbiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye

Background: Data from the onset of the Coronavirus Disease 2019 (COVID-19) pandemic has revealed a broad spectrum of clinical conditions and comorbidities. Secondary infec-tions, such as sinonasal mucormycosis, have become more frequent due to COVID-19-related immunosuppression and its subsequent treatments. Skull base osteomyelitis is another potentially fatal infection that is prevalent among immunocompromised individuals. An-giotensin-Converting Enzyme 2 (ACE2) receptors in the external auditory canal may also be implicated in cases of external otitis linked to COVID-19.
Case Report: This report discusses two cases of treatment-resistant external otitis and skull base osteomyelitis in two elderly, immunosuppressed patients (with diabetes mellitus and chronic renal failure) who had previously been treated for COVID-19. In both cases, neither topical nor intravenous antibiotic treatments were effective, leading to referrals for hyper-baric oxygen therapy.
Conclusion: For patients exhibiting persistent ear discharge and a history of COVID-19, it is imperative to avoid underestimating a potential diagnosis of skull base osteomyelitis and to pursue early imaging.

Keywords: Skull base osteomyelitis, COVID-19, otitis externa, external ear, ear infection.

Emel Tahir, Heval Can Bilek, Emre Demirel, Sinan Atmaca. Skull Base Osteomyelitis Complicating COVID-19: A Novel Secondary Infection?. J Clin Pract Res. 2023; 45(6): 651-654

Corresponding Author: Emel Tahir, Türkiye
Manuscript Language: English
LookUs & Online Makale