Background: In this report, we present two cases of coronavirus disease (COVID-19)-related acute myocarditis (AM) with different clinical presentations and electrocardiographic (ECG) findings.
Case Report: The first case was a 33-year-old male patient who presented with chest pain to the emergency department (ED). The ECG result suggested an acute coronary syndrome (ACS). However, coronary angiography (CAG) results showed normal coronary arteries, and the cardiac magnetic resonance imaging findings were compatible with COVID-19-induced AM. The ECG revealed a normalization of the T-wave negativity in the anterolateral precordial leads. The second case was a 41-year-old female patient who presented with ST-elevation myocardial infarction (STEMI) to the ED. CAG revealed normal coronary arteries, and the reverse-transcription polymerase chain reaction test result for COVID-19 was positive. The patient was diagnosed as having COVID-19-induced AM.
Conclusion: Our cases demonstrate that clinicians should be aware that some patients with COVID-19-induced AM can present with ECG findings mimicking ACS, including STEMI.