Immun thrombocytopenic purpura as sole manifestation in a case of acute hepatitis A
1Department of Neanotology, Erciyes University Medical Faculty, Kayseri, Turkey
2Department of Pediatric Hematology, Erciyes University Medical Faculty, Kayseri, Turkey
3Department of Pediatrics, Erciyes University Medical Faculty, Kayseri, Turkey
J Clin Pract Res 2008; 30(3): 198-200
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Abstract

Acute hepatitis due to hepatitis A virus is usually a benign selflimiting disease during childhood. Although many viral infections such as hepatitis B virus, Parvovirus, and Epstein-Barr virus are associated with extrahepatic autoimmune phenomena, such manifestations are rare in patients with acute hepatitis A infection. Immune thrombocytopenic purpura is rarely reported as a manifestation of acute hepatitis A. We report 11-year-old boy with immune thrombocytopenic purpura as the sole manifestation of anicteric acute hepatitis A infection. Acute hepatitis A should be included in the differential diagnosis of immune thrombocytopenic purpura.


İmmün Trombositopenik Purpuranın Tek Bulgu Olduğu Akut Hepatit A Olgusu
1Department of Neanotology, Erciyes University Medical Faculty, Kayseri, Turkey
2Department of Pediatric Hematology, Erciyes University Medical Faculty, Kayseri, Turkey
3Department of Pediatrics, Erciyes University Medical Faculty, Kayseri, Turkey
Journal of Clinical Practice and Research 2008; 3(30): 198-200

Hepatit A virüsüne bağlı akut hepatit, çocukluk çağında genellikle kendi kendini sınırlayan ve iyileşen bir hastalıktır. Hepatit B virüsü, Parvovirus, Ebstein-Barr virus enfeksiyonları gibi birçok viral enfeksiyon, ekstrahepatik otoimmun fenomenle ilişkili olmasına rağmen, akut hepatit A enfeksiyonlu hastalarda ekstrahepatik otoimmun bulgular nadirdir. İmmun trombositopenik purpura akut hepatit A enfeksiyonu bulgusu olarak nadiren bildirilmiştir. İmmun trombositopenik purpuranın tek bulgu olduğu anikterik akut hepatit A enfeksiyonlu 11 yaşında erkek olgu sunulmuştur. Akut hepatit A enfeksiyonunun ayırıcı tanısında immun trombositopenik purpura da düşünülmelidir.