The Retroconversion of Immature Teratoma with Chemotherapy: A Case Report and Review of the Literature
1Department of Medical Oncology, Erciyes University Faculty of Medicine, Kayseri, Turkey
2Department of Internal Medicine, Erciyes University Faculty of Medicine, Kayseri, Turkey
3Department of Pathology, Erciyes University Faculty of Medicine, Kayseri, Turkey
J Clin Pract Res 2014; 36(3): 136-138 DOI: 10.5152/etd.2013.66
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Abstract

Immature ovarian teratoma is a rarely seen germ cell tumor. Although testicular germ cell tumors and their association with chemotherapeutic retroconversion have been reported at a substantial rate of 2%-8% in the literature, the retroconversion of immature ovarian teratoma to mature teratoma is quite uncommon. It is important to reveal this conversion by biopsy for establishing a subsequent treatment chart of patients. A 45-year-old female patient was operated on due to immature ovarian teratoma. Then, she was re-operated on, because local recurrence occurred during the drug-free follow-up period, and systemic chemotherapy was administered. Liver metastasis was detected after chemotherapy, and the liver biopsy demonstrated a mature teratoma. This case is presented in this paper.