2Department of Gastroenterology Atatürk University Medical Faculty, Erzurum, Turkey
3Deparment of Pathology, Atatürk University, Erzurum, Turkey
Abstract
Hepatoid adenocarcinoma is a rare variant of adenocarcinoma of the stomach with a very poor prognosis. Hepatoid adenocarcinoma is characterized by a distinct morphology and immunohistochemistry, clinically characterized by the increased level of serum alpha fetoprotein. Microscopic findings include both adenocarcinomatous and hepatoid elements. The diagnosis of hepatoid adenocarcinoma of stomach is not dependent on whether alpha fetoprotein is produced; actually, histological features are important for diagnosis.
2Department of Gastroenterology Atatürk University Medical Faculty, Erzurum, Turkey
3Deparment of Pathology, Atatürk University, Erzurum, Turkey
Hepatoid adenokarsinom, midenin kötü prognozlu nadir bir adenokarsinom formudur. Hepatoid adenokarsinom farklı morfoloji ve immunohistokimya, klinik olarak artmış serum alfa fetoprotein düzeyleri ile karakterizedir. Mikroskobik bulgular hem adenokarsinom hem de hepatoid elementleri içerir. Midenin hepatoid adenokarsinom tanısı alfa fetoprotein üretip üretmediğine bağlı değildir; gerçekte, tanı için histolojik özellikler önemlidir.