Anti-GQ1b Negative Miller Fisher Syndrome Mimicking Acute Sphenoid Sinusitis
1Department of Otorhinolaryngology-Head & Neck Surgery, Hospital Tuanku Ja’afar Seremban, Negeri Sembilan, Malaysia
2Department of Otorhinolaryngology-Head & Neck Surgery, Faculty of Medicine Universiti Malaya, Kuala Lumpur, Malaysia
J Clin Pract Res 2023; 45(3): 307-309 DOI: 10.14744/etd.2022.80932
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Background: Miller Fisher Syndrome is a variant of Guillain-Barre Syndrome, classically characterized by the triad of ataxia, areflexia and ophthalmoplegia. However, many conditions can mask the presentation of Miller Fisher Syndrome, potentially leading to grave consequences due to delayed diagnosis or even misdiagnosis.
Case Report: We describe a case of Miller Fisher Syndrome mimicking acute sphenoid sinusitis with intracranial com-plications in an otherwise healthy 19-year-old man. Accurate diagnosis with prompt treatment led to full clinical recovery of our patient.
Conclusion: Sphenoid sinusitis warrants great vigilance and thorough neurological examination due to its proximity to struc-tures such as the cavernous sinus and its associated cranial nerves. This case highlights its potential to mask more devastating conditions like Miller Fisher Syndrome and the successful role of medical management without the need for sphenoidotomy.