2Department of Neurology, Dicle University Faculty of Medicine, Diyarbakir, Türkiye
3Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Abstract
Background: The simultaneous occurrence of Parkinson’s disease (PD)—a progressive neurodegenerative disorder marked by the loss of monoaminergic neurons in the substantia nigra—and Myasthenia gravis (MG)—a neuromuscular junction disease—is exceptionally rare. Although these conditions have different pathophysiological foundations, literature reports at least 29 cases of individuals diagnosed with both disorders.
Case Report: We present the case of a 66-year-old patient treated for Parkinson’s disease for four years before being diagnosed with MG, following the onset of dysphagia and bilateral ptosis. Apomorphine infusion, an advanced treatment option, was safely initiated.
Conclusion: This case highlights the coexistence of PD and MG and illustrates the potential benefits of apomorphine infusion therapy. Apomorphine was effective in reducing symptoms, improving motor function, and enhancing the patient’s quality of life.