Plasmodium Vivax Malaria Causing Cardiomyopathy and Thrombotic Microangiopathy: A Rare Association
1Sharma University Faculty of Health Sciences, Haryana, India
J Clin Pract Res 2018; 40(4): 237-239 DOI: 10.5152/etd.2018.18085
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Abstract

We report a case of dual comorbidities of thrombotic microangiopathy (TMA) and cardiomyopathy associated with Plasmo- dium vivax malaria. A 20-year-old girl presented with worsening anemia, persistent thrombocytopenia, acute kidney injury, and sinus bradycardia with ST–T changes. Hemolytic uremic syndrome was diagnosed based on schistocytes on peripheral blood lm, increased serum lactate dehydrogenase, and elevated reticulocyte production index. Kidney biopsy revealed TMA. Echocardiography initially revealed dilated cardiomyopathy with low ejection fraction that improved to normal on follow-up. The patient was kept on maintenance hemodialysis during acute illness, and later she became dialysis dependent. She has now been advised for renal transplantation.