Effect of ABO Blood Groups on Patent Ductus Arteriosus Closure
1Department of Neonatology, NICU, Ankara City Hospital, University of Health Sciences, Ankara, Turkey
J Clin Pract Res 2022; 44(3): 330-333 DOI: 10.14744/etd.2021.23855
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Abstract

Objective: Although some ABO blood groups are known to be associated with risk in adult diseases, the data related to neonatal diseases remain insufficient. The aim of this study was to identify blood groups that may confer a risk of patent ductus arteriosus (PDA) in very low birth weight (VLBW; <1500 g) preterm infants.
Materials and Methods: The records of preterm infants admitted to our unit who weighed <1500 g at birth were reviewed ret-rospectively. The prevalence of PDA and the demographic and clinical characteristics were compared according to blood group.
Results: The study included a total of 497 infants: 155 (31.2%) in blood group O, 227 (45.7%) in blood group A, 83 (16.7%) in blood group B, and 32 (6.4%) in blood group AB. There were no significant differences in PDA, demographic characteristics, or clinical parameters according to blood group (p>0.05).
Conclusion: The results of this study did not suggest a relationship between PDA and blood group in VLBW infants. These findings represent a valuable first contribution to the literature on the role of blood group in premature infants.