Objective: Seborrheic dermatitis is common in the 14–50 age group, especially the adolescent age group. It was determined that the ratio of finger lengths did not change in the adult period after being determined in the intrauterine period. At the same time, the ratio of the index finger length to the ring finger length (2D: 4D) is opposite to that of the serum testosterone. Based on this two basic knowledge, the intrauterine hormonal effect that an individual has been exposed to at any age can be determined. In our study, it was aimed to investigate the relationship between 2D: 4D finger length ratio, which is an indicator of intrauterine androgen exposure, and seborrheic dermatitis, in which androgens are accused in etiology.
Materials and Methods: Our study was planned as a descriptive and cross-sectional study among patients who applied to the dermatology outpatient clinic. Seborrheic dermatitis cases and age- and gender-matched healthy volunteers who applied to the dermatology outpatient clinic without seborrheic dermatitis were included in the study.
Results: In the evaluation made separately for both sexes; while it was observed that both females and males with seborrheic dermatitis group had a lower 2D: 4D finger length ratio compared to the control group, this was only significant in the left 2D: 4D finger length ratio in males.
Conclusion: To the best of our knowledge, there is no study in both sexes that evaluate the relationship between seborrheic dermatitis and 2D: 4D finger length ratio in the literature. Our findings support the idea that intrauterine androgen exposure may be effective in the development of seborrheic dermatitis, and larger studies are needed.