Sugammadex and Genaral Anesthesia in Two Pediatric Patients with Joubert Syndrome: Case Report
1Department of Oral Maxillofacial Surgery, Erciyes University Faculty of Dentistry, Kayseri, Turkey
2Department of Anesthesiology, Private Doğan Hospital, İstanbul, Turkey
3Department of Pediatric Dentistry, Erciyes University Faculty of Dentistry, Kayseri, Turkey
4Division of Pediatric Neurology, Department of Pediatrics, Erciyes University Faculty of Medicine, Kayseri, Turkey
J Clin Pract Res 2017; 39(1): 35-36 DOI: 10.5152/etd.2017.16108
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Abstract

Joubert syndrome (JS) is a rare genetic disorder that affects the cerebellum, controlling balance, and coordination, and it usually presents a molar tooth sign on magnetic resonance imaging. It is characterized by ataxia, an abnormal breathing pattern referred to as hyperpnea, sleep apnea, hypotonia, and abnormal eye and tongue movements. Because of sensitivity to respiratory depressant agents, including opiates, nitrous oxide, and neuromuscular blockers, and potential difficult airways, anesthetic management requires attention. Sugammadex binds to rocuronium and is a reverse neuromuscular blocker. In this study, two cases of JS where sugammadex was used for general anesthesia are presented. Sugammadex may be a safe general anesthetic for patients with JS.