Review
Next-Generation DNA Sequencing Technologies
1Department of Medical Biology, Hacettepe University Faculty of Medicine, Ankara, Turkey
J Clin Pract Res 2014; 36(3): 99-103 DOI: 10.5152/etd.2014.7803
Abstract
Recently, the requirement for fast, low-cost, and highly reliable methods has triggered the development of next-generation DNA sequencing technologies. In addition to overcoming the restrictions in Sanger sequencing methods, large-scale genetic data have provided the development of different analysis methods. In this paper, widely used next-generation sequencing platforms, the analyses of the data obtained, and the applications of these technologies are discussed.
Keywords: Genome, next-generation sequencing, high-throughput sequencing