Objective: This study aims to examine the platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) values in predicting mortality of Crimean-Congo Hemorrhagic Fever (CCHF) patients in an intensive care unit (ICU).
Materials and Methods: This is a retrospective study, and 34 patients diagnosed with CCHF hospitalized in ICU between 1 January 2016–1 January 2020 were included in this study. Demographic data and PLR, NLR, mean platelet volume (MPV), red cell distribution width (RDW), c-reactive protein (CRP) values in their first blood samples taken in ICU were analyzed. Receiver operating characteristic (ROC) curve analyses for the estimation value of the parameters was carried out. The area under the curve (AUC), sensitivity and specificity were used to evaluate the performance of the diagnostic tests.
Results: The mortality rate was 52% (18 exitus). The average length of ICU stay was 10.8±6.6 days. For the value of 8.40 FL for MPV, sensitivity was 83.3%, and specificity was 68.8%. The sensitivity was 88.9% and the specificity was 81.3% for the value of 13.15% of RDW. For NLR, the sensitivity was 83.3%; and the specificity was 87.5% for the value of 2.73. For PLR, the sensitivity was 81.3%, and the specificity was 100% for the cut-off value of 49.94.
Conclusion: PLR and NLR can give the physician an idea about the mortality in patients with severe CCHF; however, studies with a larger number of patients are needed for full validity.